Publication

100

Jung-Eun Kim, Keunok Jung, Jeong-Ah Kim, Seung-Hyun Kim, Hae-Sim Park and Yong-Sung Kim* (2019) 

Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity.

Scientific Reports, 2019 May, 9:7772.

99

Yeo Wool Kang, Ji Eun Lee, Kyung Hee Jung, Mi Kwon Son, Seung-Min Shin, Soo Jung Kim, Zhenghuan Fang, Hong Hua Yan, Jung Hee Park, Boreum Han, Min Ji Cheon, Min Gyu Woo, Joo Han Lim, Yong-Sung Kim*, Soon-Sun Hong* (2018) 

KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer

Cancer Letters, 2018 December, 438:174-186.

98

Bok-Soon Lee, Yeon Soo Kim, Haeng Jun Kim, Dae Ho Kim, Ho-Ryun Won, Yong-Sung Kim, and Chul-Ho Kim* (2018) 

HDAC4 degradation by combined TRAIL and valproic acid treatment induces apoptotic cell death of TRAIL-resistant head and neck cancer cells.

Scientific Reports, 2018 Aug 21;8(1):12520.

97

Ji-sun Kim, Jae-Yeong Park, Seung-Min Shin, Seong-Wook Park, Sei-Yong Jun, Jin-Sun Hong, Dong-Ki Choi, Yong-Sung Kim* (2018) 

Engineering of a tumor cell–specific, cytosol-penetrating antibody with high endosomal escape efficacy.

Biochem Biophys Res Commun, 2018. September 18; 503(4):2510-2516.

96

Chongtae Kim, Da Eun Jeong, Sungeun Heo, Eunbyul Ji, Jun Gi Rho, Myeongwoo Jung, Sojin Ahn, Ye-Jin Kim, Yong-Sung Kim, Suk Woo Nam, Rohit N. Kulkarni, Kyoung Bun Lee, Eun Kyung Lee and Wook Kim* (2018)

Reduced RNA-binding protein HuD in pancreatic neuroendocrine tumors lowers p27Kip1 levels linked to poor prognosis.

The Journal of Pathology, 2018 October, 246:231-243.

95

Keunok Jung, Ji-Hee Ha, Jung-Eun Kim, Jeong-Ah Kim, Ye-Jin Kim, Chul-Ho Kim, and Yong-Sung Kim* (2018) 

Heterodimeric Fc-fused IL12 shows potent antitumor activity by generating memory CD8+ T cells.

Oncoimmunology, 2018 March 6, 7:7, e1438800.

94

Du-San Baek, Jeong-Ho Kim, Ye-Jin Kim, and Yong-Sung Kim* (2018)

Immunoglobulin Fc-fused Peptide without C-terminal Arg or Lys Residue Augments Neuropilin-1-dependent Tumor Vascular Permeability.

Molecular Pharmaceutics, 2018 Feb 5;15(2):394-402.

93

Jeong-Ho Kim, Woo-Young Seo, Du-San Beak, Su-Jung Kim, Su-Jin Kang, Won Suk Yang, Ji-Ae Song, 

Moo-Seung Lee, Sunghoon Kim* and Yong-Sung Kim* (2017)

Production of recombinant human procollagen type I C-terminal propeptide and establishment of a sandwich ELISA for quantification.

Scientific Reports, 2017. 7:15946.

92

Seung-Min Shin, Dong-Ki Choi, Keunok Jung, Jeomil Bae, Ji-sun Kim, Seong-wook Park, Ki-Hoon Song,

and Yong-Sung Kim* (2017)

Antibody targeting intracellular oncogenic Ras mutants exerts anti-tumor effects after systemic administration.

Nature Communications, 2017. 8:15090. 

91

Siyoung Lee, Dong-Ki Choi, Areum Kwak, Sinae Kim, Tam Thanh Nguyen, Gaae Gil, Eunhye Kim, Kwang Ha Yoo, In Ae Kim, Youngmin Lee, Hyunjhung Jhun, Edward D. Chan, Xiyuan Bai, Hyunwoo Kim, Yong-Sung Kim, and Soohyun Kim* (2017)

IL-32 induced Inflammatory Cytokines Are Selectively Suppressed by α1-antitrypsin in Mouse Bone Marrow Cells.

Immune Network, 2017 April;17(2):116-120.

90

Ye-Jin Kim, Keunok Jung, Du-San Baek, Soon-Sun Hong, and Yong-Sung Kim* (2017)

Co-targeting of EGF Receptor and Neuropilin-1 Overcomes Cetuximab Resistance in Pancreatic Ductal Adenocarcinoma with Integrin β1-driven Src-Akt Bypass Signaling. 

Oncogene, 2017 May, 4;36(18):2543-2552.

89

Guang Wu, Dongbum Kim, Byoung Kwon Park, Sangkyu Park, Ji-Hee Ha, Te Ha Kim, Avishekh Gautam, Jung Nam Kim, Su In Lee, Han-Bum Park, Yong-Sung Kim, Hyung-Joo Kwon*, Younghee Lee* (2016)

Anti-metastatic effect of the TM4SF5-specific peptide vaccine and humanized monoclonal antibody on colon cancer in a mouse lung metastasis model. 

Oncotarget, 2016 December, 7(48):79170-79186

88

Ji-Hee Ha, Jung-Eun Kim, and Yong-Sung Kim* (2016)

Immunoglobulin Fc heterodimer platform technology: From design to applications in therapeutic antibodies and proteins. 

Frontiers in Immunology, 2016 October, 7:394.

87

Ji-Sun Kim, Dong-Ki Choi, Ju-Yeon Shin, Seung-Min Shin, Seong-Wook Park, Hyun-Soo Cho, Yong-Sung Kim* (2016)

Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape.

Journal of Controlled Release, 2016. Aug 10, 235:165-175.

86

Siyoung Lee, Eunsom Kim, Hyunjhung Jhun, Jaewoo Hong, Areum Kwak, Seunghyun Jo, Suyoung Bae, Jong Lee, Busun Kim, Jungmin Lee, Sulah Youn, Somi Kim, Miyeon Kim, Hyunwoo Kim, Youngmin Lee, Dong-Ki Choi, Yong-Sung Kim, Soo Hyun Kim* (2016)

Proinsulin shares a motif with IL-1α and induces inflammatory cytokine via interleukin-1 receptor 1.

The Journal of Biological Chemistry, 2016. Jul 8;291(28):14620-14627.

85

Seung Eui Min, Kyung-Ho Lee, Seong-Wook Park, Tae Hyun Yoo, Chan Hee Oh, Ji-Ho Park, Sung Yun Yang, Yong-Sung Kim, and Dong-Myung Kim* (2016)

Cell-free production and streamlined assay of cytosol-penetrating antibodies.

Biotechnology and Bioengineering, 2016. Oct;113(10):2107-2112.

84

Seunghyun Jo, Eunsom Kim, Areum Kwak, Jungmin Lee, Jaewoo Hong, Jongho Lee, Sulah Youn, Suyoung Bae, Busun Kim, Soyoon Ryoo, Tae-Bong Kang, Erk Her, Dong-Ki Choi, Yong-Sung Kim, Youngmin Lee, Hyunjhung Jhun, and Soohyun Kim* (2016)

Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Rα though a common chain IL-1R3 (IL-1RAcP) shared with IL-1.

Cytokine, 2016 Mar 28; 83:33-40.

83

Suk-Youl Park, Bo-Na Kim, Dong-Ki Choi, Pil-Won Seo, Do-Heon Gu, Yong-Sung Kim and Jeong-Sun Kim* (2016)

Crystal structure and its proposed nucleolytic site of the single domain catalytic antibody 3D8-VH.

Biodesign, 2016 Mar 30; 4(1): 25-30.

82

Dongbum Kim , Te Ha Kim , Guang Wu, Byoung Kwon Park, Ji-Hee Ha, Yong-Sung Kim, Keunwook Lee, Younghee Lee, Hyung-Joo Kwon* (2016)

Extracellular Release of CD11b by TLR9 Stimulation in Macrophages.

PLoS One, 2016 Mar 8;11(3):e0150677.

81

Hyun-Young Cha, Bok-Soon Lee, Jae Won Chang, Ju Kyeong Park, Jae Ho Han, Yong-Sung Kim, Yoo Seob Shin, Hyung Kwon Byeon, Chul-Ho Kim* (2016)

Downregulation of Nrf2 by the combination of TRAIL and Valproic acid induces apoptotic cell death of TRAIL-resistant papillary thyroid cancer cells via suppression of Bcl-xL.

Cancer Letters, 2016 Mar 1, 372(1): 65-74.