Eun-Sil Sung, Kyung-Jin Park, Hye-Ji Choi, Chul-Ho Kim, Yong-Sung Kim* (2012)

The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.

Experimental Cell Research, 2012 Aug 1, 318:(13) 1564-1576.


Bok-Soon Lee, Sung Un Kang, Hye Sook Hwang, Yong-Sung Kim, Eun-Sil Sung, Yoo Seob Shin, Young Chang Lim, Chul-Ho Kim*(2012)

An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation.

Cancer Letters, 2012 Sep 1, 332(1):45-57.


Aeyung Kim, Ja-Yeong Lee, Sung June Byun, Myung-Hee Kwon, Yong-Sung Kim* (2012)

Viral genome RNA degradation by sequence-selective, nucleic-acid hydrolyzing antibody inhibits the replication of influenza H9N2 virus without significant cytotoxicity to host cells.

Antiviral Research, 2012 May, 94(2):157-167.


Aeyung Kim, Dong-Ki Choi, Eun-Sil Sung, Jee Sun Yun, Myung-Hee Kwon, and Yong-Sung Kim* (2012)

Interfering transbody-mediated Her2 gene silencing induces apoptosis by G0/G1 cell cycle arrest in Her2-overexpressing SK-BR-3 breast cancer cells.

Biotechnology and Bioprocess Engineering, 2012 Apr, 17:413-419.


Kyung-Jin Park, Chang-Han Lee, Aeyung Kim, Ki Jun Jeong, Chul-Ho Kim, and Yong-Sung Kim* (2012)

Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death.

Journal of Biological Chemistry, 2012 Jan 27, 287(5):3313-3325.


Gil-Yong Lee, Jong-Hyun Jung, Dong-Ho Seo, Jantra Hansin, Suk-Jin Ha, Jaeho Cha, Yong-Sung Kim, Cheon-Seok Park* (2011)

Isomaltulose production via yeast surface display of sucrose isomerase from Enterobacter sp. FMB1 on Saccharomyces cerevisiae

Bioresource Technology, 2011 Oct, 102(19):9179-9184.


Seung Hoon Jang, Chang Han Lee, Yong Sung Kim, and Ki Jun Jeong* (2011)

High-level production of a kringle domain variant by high-cell-density cultivation of Escherichia coli.

Applied Microbiology and Biotechnology, 2011 Oct, 92(2):327-336.


Chang-Han Lee, Kyung-Jin Park, Sang Jick Kim, Ohsuk Kwon, Ki Jun Jeong, Ayeung Kim, and Yong-Sung Kim* (2011)

Generation of bivalent and bispecific Kringle single domains by loop grafting as potent agonists against death receptor 4 and 5.

Journal of Molecular Biology, 2011 Aug 5, 411 (1):201-219.


Jong-Geun Jeong, Dong-Sik Kim, Yong-Sung Kim, Myung-Hee Kwon* (2011)

A Tat-grafted anti-nucleic acid antibody acquires nuclear-localization property and a preference for TAR RNA.

Biochemical and Biophysical Research Communications, 2011 Mar 18, 406 (3):403-407.


Soomin Yoon, Yong-Sung Kim, Hyunbo Shim, and Junho Chung (2010)

Current Perspectives on Therapeutic Antibodies.

Biotechnology and Bioprocess Engineering, 2010 Oct 31, 15 (5):709-715.


Eun-Sil Sung, Aeyung Kim, Joon Seong Park, Junho Chung, Myung-Hee Kwon, Yong-Sung Kim* (2010)

Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells.

Apoptosis, 2010 Oct 15, 10:1256-1269.


Chang-Han Lee, Kyung-Jin Park, Eun-Sil Sung, Aeyung Kim, Ji-Da Choi, Jeong-Sun Kim, Soo-Hyun Kim, Myung-Hee Kwon, Yong-Sung Kim* (2010)

Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo.

Proceedings of the National Academy of Sciences, 2010 May 11, 107:9567-9571.


Hye-Ryeong Jun, Chuong D. Pham, Seong-In Lim, Suk-Chan Lee, Yong-Sung Kim, Sun Park and Myung-Hee Kwon* (2010)

An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus.

Biochemical and Biophysical Research Communications. 2010 Apr 9, 395:484-489.


Chang-Han Lee, Dong-Ki Choi, Hye-Ji Choi, Moo-Young Song, and Yong-Sung Kim* (2010)

Expression of soluble and functional human neonatal Fc receptor in Pichia pastoris.

Protein Expression and Purification, 2010 May 1, 71:42-48.


Woo-Ram Lee, Ji-Young Jang, Jeong-Sun Kim, Myung-Hee Kwon and Yong-Sung Kim* (2010)

Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies.

Nucleic Acids Research, 2010 Mar 5, 38:1596-1609.


Kwang-Won Hong, Chang-Goo Kim, Seung-Hyun Lee, Ki-Hwan Chang, Yong Won Shin, Kyung-Hwan Ryoo, Se-Ho Kim* and Yong-Sung Kim*(2010)

A novel anti-EGFR monoclonal antibody inhibiting tumor cell growth by recognizing different epitope from cetuximab.

Journal of Biotechnology, 2010 Jan 1, 145:84-91.


Seung-Hyun Lee, Dong-Woon Park, Eun-Sil Sung, Hye-Ran Park, Jin-Kyoo Kim, and Yong-Sung Kim* (2010)

Humanization of an agonistic anti-death receptor 4 single chain variable fragment antibody and avidity-mediated enhancement of its cell death-inducing activity.

Molecular Immunology, 2010 Jan 2, 47:816-824.


Yuchul Jung, Yong Rhee, Chung-Kyoon Auh, HyeKyung Shim, Jung-Jin Choi, Suk-Tae Kwon, Joo-Sung Yang, Donggiun Kim, Myung-Hee Kwon, Yong-Sung Kim, Sukchan Lee (2009)

Production of recombinant single chain antibodies (scFv) in vegetatively reproductive Kalanchoe pinnata by in planta transformation.

Plant Cell Report, 2009 Aug 18, 28:1593-1602.


Eun-Sil Sung, Kyung-Jin Park, Seung-Hyun Lee, Yoon-Seon Jang, Sang-Koo Park, Yoo-Hoi Park, Won-Jae Kwag, Myung-Hee Kwon, and Yong-Sung Kim* (2009)

A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes.

Molecular Cancer Therapeutics, 2009 Aug 1, 8(8):2276-85.


Ji-Young Jang, Jong-Geun Jeong, Hye-Ryong Jun, Suk-Chan Lee, Jeong-Sun Kim, Yong-Sung Kim*, and Myung-Hee Kwon* (2009)

A nucleic acid-hydrolyzing antibody penetrates into cells via Caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicity.

Cellular and Molecular Life Sciences, 2009 Jun, 66(11-12):1985-97.