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53

Chang-Han Lee, Kyung-Jin Park, Sang Jick Kim, Ohsuk Kwon, Ki Jun Jeong,

Ayeung Kim, and Yong-Sung Kim* (2011)
Generation of bivalent and bispecific Kringle single domains by loop grafting as 

potent agonists against death receptor 4 and 5.
Journal of Molecular Biology,
2011 Aug 5, 411 (1):201-219

52

Jong-Geun Jeong, Dong-Sik Kim, Yong-Sung Kim, Myung-Hee Kwon* (2011)
A Tat-grafted anti-nucleic acid antibody acquires nuclear-localization property and a

preference for TAR RNA.  
Biochemical and Biophysical Research Communications, 2011 Mar 18, 406 (3):403-407. 

51 Soomin Yoon, Yong-Sung Kim, Hyunbo Shim, and Junho Chung (2010)
Current Perspectives on Therapeutic Antibodies. 
Biotechnology and Bioprocess Engineering,
2010 Oct 31, 15 (5):709-715.
50

Eun-Sil Sung, Aeyung Kim, Joon Seong Park, Junho Chung, Myung-Hee Kwon, Yong-Sung Kim* (2010)
Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated 

apoptotic cell death of human T-cell acute lymphoblastic leukemia cells.   

Apoptosis, 2010 Oct 15, 10:1256-1269.

49

Chang-Han Lee, Kyung-Jin Park, Eun-Sil Sung, Aeyung Kim, Ji-Da Choi, Jeong-Sun Kim, Soo-Hyun Kim,

Myung-Hee Kwon, Yong-Sung Kim* (2010)
Engineering of a human kringle domain into agonistic and antagonistic binding proteins 

functioning in vitro and in vivo.

Proceedings of the National Academy of Sciences, 2010 May 11, 107:9567-9571.

48

Hye-Ryeong Jun, Chuong D. Pham, Seong-In Lim, Suk-Chan Lee, Yong-Sung Kim,

Sun Park and Myung-Hee Kwon* (2010)
An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against 

classical swine fever virus.
Biochemical and Biophysical Research Communications.
2010 Apr 9, 395:484-489.

47 Chang-Han Lee, Dong-Ki Choi, Hye-Ji Choi, Moo-Young Song, and Yong-Sung Kim* (2010)
Expression of soluble and functional human neonatal Fc receptor in Pichia pastoris. 
Protein Expression and Purification,
2010 May 1, 71:42-48.
46

Woo-Ram Lee, Ji-Young Jang, Jeong-Sun Kim, Myung-Hee Kwon and Yong-Sung Kim* (2010)
Gene silencing by cell-penetrating, sequence-selective and nucleic-acid

hydrolyzing antibodies.
Nucleic Acids Research,
2010 Mar 5, 38:1596-1609. 

45

Kwang-Won Hong, Chang-Goo Kim, Seung-Hyun Lee, Ki-Hwan Chang, Yong Won Shin,

Kyung-Hwan Ryoo, Se-Ho Kim* and Yong-Sung Kim*(2010)
A novel anti-EGFR monoclonal antibody inhibiting tumor cell growth by recognizing 

different epitope from cetuximab.
Journal of Biotechnology, 2010 Jan 1, 145:84-91.

44

Seung-Hyun Lee, Dong-Woon Park, Eun-Sil Sung, Hye-Ran Park,

Jin-Kyoo Kim, and Yong-Sung Kim* (2010)
Humanization of an agonistic anti-death receptor 4 single chain variable fragment 

antibody and avidity-mediated enhancement of its cell death-inducing activity.
Molecular Immunology,
2010 Jan 2, 47:816-824.

43

Yuchul Jung, Yong Rhee, Chung-Kyoon Auh,  HyeKyung Shim, Jung-Jin Choi, Suk-Tae Kwon,

Joo-Sung Yang, Donggiun Kim, Myung-Hee Kwon, Yong-Sung Kim, Sukchan Lee (2009)
Production of recombinant single chain antibodies (scFv) in vegetatively reproductive 

Kalanchoe pinnata by in planta transformation.
Plant Cell Report,
 2009 Aug 18, 28:1593-1602.

42

Eun-Sil Sung, Kyung-Jin Park, Seung-Hyun Lee, Yoon-Seon Jang, Sang-Koo Park, Yoo-Hoi Park,

Won-Jae Kwag, Myung-Hee Kwon, and Yong-Sung Kim* (2009)
A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in 

various tumor cells without cytotoxicity in hepatocytes.
Molecular Cancer Therapeutics, 2009 Aug 1, 8(8):2276-85.

41

Ji-Young Jang, Jong-Geun Jeong, Hye-Ryong Jun, Suk-Chan Lee, Jeong-Sun Kim,

Yong-Sung Kim*, and Myung-Hee Kwon* (2009)
A nucleic acid-hydrolyzing antibody penetrates into cells via Caveolae-mediated 

endocytosis, localizes in the cytosol and exhibits cytotoxicity.
Cellular and Molecular Life Sciences, 2009 Jun, 66(11-12):1985-97.

40

Kyung-Jin Park, Seung-Hyun Lee, Chang-Han Lee, Ji-Young Jang, Junho Chung, Myoung-Hee Kwon,

Yong-Sung Kim* (2009)
Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved 

in the JNK-mediated autophagic cell death.
Biochemical and Biophysical Research  Communications, 2009 May 15, 382(4):726-9.

39

Dong-Sik Kim, Seung-Hyun Lee, Jeong-Sun Kim, Suk-Chan Lee,

Myung-Hee Kwon, and Yong-Sung Kim* (2009)
Generation of humanized anti-DNA hydrolyzing catalytic antibodies by complementarity 

determining region grafting.
Biochemical and Biophysical Research Communications, 2009 Feb 06, 379 (2): 314-318. 

38 Sejin Son,Woo Ram Lee, Yoon Ki Joung, Myung Hee Kwon, Yong Sung Kim, Ki Dong Park* (2009)
Optimized stability retention of a monoclonal antibody in the PLGA nanoparticles.
International Journal of Pharmaceutics, 2009 Feb 23, 368 (1-2): 178-185.
37 Kim In Seop*, Yong Woon Choi, Yong Kang, Hark Mo Sung, Ki Whan Sohn, and Yong-Sung Kim (2008)
Improvement of Virus Safety of an Antihemophilic Factor by Virus Filtration Process.
Journal of Microbiology and Biotechnology, 2008 Jan, 18(7): 1317-1325.
36

Suk-Youl Park, Woo-Ram Lee, Suk-Chan Lee, Myung-Hee Kwon,

Yong-Sung Kim, and Jeong-Sun Kim* (2008)
Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv 

and its active site revealed by complex structures of a small molecule and metals.
Proteins : Structure, function, and Bioinformatics, 2008 Jun,71(4): 2091-2096.

35

Ji-Woo Choi, Jieun Lee, Kosuke Nishi, Yong-Sung Kim, Che-Hun Jung and Jeong-Sun Kim* (2008)
Crystal structure of a minimal nitroreductase, ydjA, from Escherichia coli K12 with and

without FMN cofactor.
Journal of Molecular Biology, 2008 Mar, 377 (1): 258-267.

34

Suk-Youl Park, Sang-Hak Lee, Jieun Lee, Kosuke Nishi, Yong-Sung Kim, Che-Hun Jung,

Jeong-Sun Kim* (2008)
High resolution structure of ybfF from Escherichia coli K12: a unique substrate-binding 

crevice generated by domain arrangement.
Journal of Molecular Biology, 2008 Mar 7, 376 (5): 1426-1437.